Fluorescence optical diffusion tomography
نویسندگان
چکیده
منابع مشابه
Fluorescence optical diffusion tomography.
A nonlinear, Bayesian optimization scheme is presented for reconstructing fluorescent yield and lifetime, the absorption coefficient, and the diffusion coefficient in turbid media, such as biological tissue. The method utilizes measurements at both the excitation and the emission wavelengths to reconstruct all unknown parameters. The effectiveness of the reconstruction algorithm is demonstrated...
متن کاملFluorescence optical diffusion tomography using multiple-frequency data.
A method is presented for fluorescence optical diffusion tomography in turbid media using multiple-frequency data. The method uses a frequency-domain diffusion equation model to reconstruct the fluorescent yield and lifetime by means of a Bayesian framework and an efficient, nonlinear optimizer. The method is demonstrated by using simulations and laboratory experiments to show that reconstructi...
متن کاملEstimation of kinetic model parameters in fluorescence optical diffusion tomography.
We present a technique for reconstructing the spatially dependent dynamics of a fluorescent contrast agent in turbid media. The dynamic behavior is described by linear and nonlinear parameters of a compartmental model or some other model with a deterministic functional form. The method extends our previous work in fluorescence optical diffusion tomography by parametrically reconstructing the ti...
متن کاملFluorescence lifetime optical projection tomography.
We describe a quantitative fluorescence projection tomography technique which measures the 3-D fluorescence lifetime distribution in optically cleared specimens up 1 cm in diameter. This is achieved by acquiring a series of wide-field time-gated images at different relative time delays with respect to a train of excitation pulses, at a number of projection angles. For each time delay, the 3-D t...
متن کاملMultiplexed Fluorescence Diffuse Optical Tomography
iii To my family, for their love and support. iv ACKNOWLEDGEMENTS First and foremost, I wish to thank my parents and my sister, Guiti, Leili and Alireza, for their unconditional love, support, and understanding throughout this long journey. from whom I learned the many complex aspects of molecular imaging. I wish to acknowledge my reading committee for their dedication and guidance throughout t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Applied Optics
سال: 2003
ISSN: 0003-6935,1539-4522
DOI: 10.1364/ao.42.003081